치아우식증 유발 세균에 대한 CPC 함유 구강청정제의 항균효과
Antibacterial effect of mouthwash containing CPC against dental caries caused bacteria
조원호, 조자원, 유현준, 신경훈, 신기해, 전열매, 이종천,
소속 상세정보
조원호 ( Cho Won-Ho ) - Dankook University College of Dentistry Department of Preventive Dentistry
조자원 ( Cho Ja-Won ) - Dankook University College of Dentistry Department of Preventive Dentistry
유현준 ( Yoo Hyun-Jun ) - Dankook University College of Dentistry Department of Preventive Dentistry
신경훈 ( Shin Kyong-Hoon ) - Aekyung Industrial Co., Ltd. R&D Division Dental Care Team
신기해 ( Shjn Gi-Hae ) - Aekyung Industrial Co., Ltd. R&D Division Dental Care Team
전열매 ( Jeon Yeol-Mae ) - Dankook University College of Dentistry Department of Preventive Dentistry
이종천 ( Lee Jong-Cheon ) - Dankook University College of Dentistry Department of Preventive Dentistry
Abstract
Objectives: The purpose of this study was to evaluate and report the antibacterial efficacy in relation to oral disease-causing bacteria using a mouthwash containing 0.05% CPC in an in vitro test.
Methods: The sterilization test and susceptibility assay of mouthwash containing 0.05% CPC were investigated against Streptococcus mutans, Streptococcus sobrinus, and Lactobacillus acidophilus; Streptococcus sanguinis as oral bacteria related to dental caries; Enterococcus faecalis as apical periodontitis-related bacteria; and Actinomyces israelii, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Prevotella intermedia, Prevotella nigrescence, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Filifactor alocis as periodontal disease-related bacteria.
Results: In the sterilization test, most of the bacteria had more than 99.99% sterilizing power for all samples but compared to other bacteria, the sterilizing power of these samples was not successful for L. acidophilus and E. faecalis bacteria. When comparing the sterilization power between the samples, sample 3 (0.05% CPC+20% ethanol) was the strongest.
Conclusions: In the antimicrobial activity test, sample 3 inhibited growth at the lowest concentration overall.
키워드
Cetylpyridinium chloride; Mouthwashes; Streptococcus mutans
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